How to choose a bone graft substitute for spine fusion?

What spine surgeons need to know — from a medical equipment supplier in University Hospitals Cleveland, OH.

Contact Us (440) 488-0091

You’re a spine surgeon at University Hospitals Cleveland. You’ve moved away from harvesting the patient’s own bone for fusion. Safer for the patient, but now you’re staring at dozens of synthetic graft options. Between OR schedules and value analysis meetings, you need clear criteria to pick the right one. Not another brochure.

You see shelves of calcium phosphate grafts with similar names. The difference is in the pore structure. A graft with less than 75% porosity won’t let bone grow through it. Silicate substitution is not a marketing word — it triggers the body to lay down new bone faster. Without it, the graft resorbs too slowly. For spine fusion, you need clinical fusion data at 12 months, not just a CT of a rat femur.

Cost per level varies by graft volume and delivery system. A flowable graft for MIS TLIF costs more per cc than a moldable block for PLIF. But compare that to the cost of a revision for pseudarthrosis. Autograft has zero material cost but adds harvest time and morbidity. BMP-2 is expensive and comes with FDA warnings. A silicate-substituted graft with strong spine data often wins the value equation when you factor in OR time and complication avoidance.

This week, pull the IFU for your current graft. Check porosity, silicate content, and the reference list for spine-specific studies. If the data isn’t there, ask your Elite Surgical rep for ACTIFUSE or ALTAPORE clinical summaries. Both are available in formats to match your approach — syringe for MIS, moldable strip for open, morsels for packing. Request an in-service and feel the handling yourself. No sales pitch, just the evidence and a trial.

You walk into the OR with a graft you can trust. The delivery tool fits your hands. The fusion progresses on your 6-month CT. Your value analysis team sees the peer-reviewed data and signs off. You stop wasting time comparing claims and get back to planning fusions you’re confident will take. The patient walks without pain, and you walk out of the OR on time.

Authorized distributor of Baxter ACTIFUSE
93% fusion across 694 patients, independent review
FDA cleared and used in US spine surgery since 2007

Other things people in University Hospitals Cleveland ask

autograft vs synthetic bone graft substitute

Modern synthetic bone graft substitutes like ACTIFUSE and ALTAPORE show fusion rates comparable to autograft without donor site morbidity. Synthetics eliminate harvest time and reduce patient pain. Consider synthetic for single-level fusions, combine with autograft for complex cases.

bone graft substitute not integrating

Poor integration often comes from low porosity or inadequate bioactivity in the graft material. Switch to a silicate-substituted calcium phosphate with 80%+ porosity like ACTIFUSE or ALTAPORE. The enhanced porosity allows better bone ingrowth and vascularization.

consistent bone graft substitute results

Consistent results need consistent material quality and technique. Use bone graft substitutes with proven fusion rates like ALTAPORE's 86.3% rate. Ensure proper hydration, avoid overpacking, and maintain sterile handling. Elite Surgical provides technique guides for optimal results.

bone graft substitute syringe clogging

Clogging usually means the particle size is wrong for the delivery system or the material is too thick. ACTIFUSE FLOW is specifically designed for syringe delivery with consistent particle size. ACTIFUSE MIS offers minimally invasive delivery without clogging issues.

when to use bone graft substitute vs allograft

Use synthetic bone graft substitutes like ACTIFUSE when you want consistent quality without disease transmission risk. Allograft works for structural support in large defects. Synthetics are better for biological fusion enhancement in routine cases.

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